Oxygen-regulated Expression of TGF-β3, a Growth Factor Involved in Trophoblast Differentiation
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چکیده
منابع مشابه
Expression of TGF-β3 in Isolated Fibroblasts from Foreskin
Background: The multifunctional transforming growth factor beta (TGF-β) is a glycoprotein that exists in three isoforms. TGF-β3 expression increases in fetal wound healing and reduces fibronectin and collagen I and III deposition, and also improves the architecture of the neodermis which is a combination of blood vessels and connective tissue during wound healing. Fibroblasts are key ...
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Background: Several studies have shown that leukemia inhibitory factor (LIF) is one of the most important cytokinesparticipating in the process of embryo implantation and pregnancy, while, the role of this factor on vascular endothelialfactor-A (VEGF-A), as one of the most important angiogenic factor, has not been fully investigated yet. The aimof this study was to evaluate th...
متن کاملexpression of tgf-β3 in isolated fibroblasts from foreskin
background: the multifunctional transforming growth factor beta (tgf-β) is a glycoprotein that exists in three isoforms. tgf-β3 expression increases in fetal wound healing and reduces fibronectin and collagen i and iii deposition, and also improves the architecture of the neodermis which is a combination of blood vessels and connective tissue during wound healing. fibroblasts are key cells in t...
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Objective Adult stem cells which are derived from different tissues, with their unique abilities to self-renew and differentiate into various phenotypes have the potential for cell therapy and tissue engineering. Human adipose tissue is an appropriate source of mesenchymal stem cells with wide differentiation potential for tissue engineering research. In this study isolated stem cells from hum...
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Nerve growth factor (NGF) stimulation of pheochromocytoma PC12 cells transiently increased the intracellular concentration of reactive oxygen species (ROS). This increase was blocked by the chemical antioxidant N-acetylcysteine and a flavoprotein inhibitor, diphenylene iodonium. NGF responses of PC12 cells, including neurite outgrowth, tyrosine phosphorylation, and AP-1 activation, was inhibite...
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ژورنال
عنوان ژورنال: Placenta
سال: 2003
ISSN: 0143-4004
DOI: 10.1016/s0143-4004(03)00166-8